Figure 3

FIRE analysis for transcriptional regulatory motifs occurring in the clusters presented in figure 2. For each cluster, the most significant GO enrichments are shown at the top. Yellow indicates over-representation of a motif in a given cluster and significant (p < 0.05) overrepresentation is highlighted with red frames. Similarly, blue blocks and blue frames indicate significant (p < 0.05) under-representation. For each motif, the location (either 5' upstream or 3' UTR), mutual information (MI) value, Z score associated with the MI value, a robustness score ranging from 1/10 to 10/10, a position bias indicator ("Y" indicates position bias is observed), orientation bias indicator, conservation index, the seed that gave rise to the motif and name of the closest known motif are presented. For more details, see Elemento and co-workers 2007 [35].