Figure 2
Microarray screening of detoxifications genes differentially transcribed in the insecticide-resistant strain Vauclin. Differential transcription of detoxification gens was investigated separately in 4th-stage larvae (A) and 3-days old adults (B). For each life stage, differences in gene transcription are indicated as a function of both transcription ratio (Vauclin/Bora-Bora) and ratio's significance (t-test P values). For each comparison, only probes showing consistent data in at least 3 hybridisations out of 6 were considered. Vertical lines indicate 1.5-fold transcription difference in either direction. Horizontal line indicates significance threshold (p < 0.01) adopted for the one sample t-test after Benjamini and Hochberg multiple testing correction procedure. Probes showing both more than 1.5-fold differential transcription and a significant P value are named. Probes that were found under- or over-transcribed in both larvae and adults are shown in bold. Suffixes a and b represent two different probes of the same gene while suffixes v1 and v2 represent two different alleles of the same gene.