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Table 4 Lists of differentially expressed genes involved in cellular and molecular functions regulated in intestinal epithelial cells by enteric glial cells.

From: Regulation of intestinal epithelial cells transcriptome by enteric glial cells: impact on intestinal epithelial barrier functions

Ingenuity© cellular and molecular functions Genes list Score
RNA Post-Transcriptional Modification NOP5/NOP58, NOL5A, EBNA1BP2, RNU3IP2, IMP3 5.17
Cell Death GPX2, SAT, PRKCD, B4GALT5, TXNIP, TOP2A, CDH1, PKN2, ASAH1, LSP1, BNIP3L, NPPB, CDK5R1, ANKRD1, VIP, CASP4, GLRX, FGFR2, KRT18, BAG1, PRKCQ, BTG1, PPARG, C6ORF66, SLC2A1, CARD12, SMAD3, FTH1, LAMA5, PTK2, IL18, MLLT3, FN1, PLAC8, KRT8, TGFBI, BNIP3, E2F1, SFRP4 4.85
Cell-To-Cell Signaling and Interaction APOH, PRKCD, SMAD3, CDH1, PKN2, LAMA5, PTK2, VIP, IL18, FN1, FGG, KRT8, KRT18, BAG1, ITGAE, LAMC1, PPARG, TGFBI, E2F1 3.92
Cellular Development SMAD3, PRKCD, CDH1, LAMA5, VIP, PTK2, IL18, CDK5R1, FGFR2, FN1, PLAC8, PRKCQ, LAMC1, PPARG, E2F1 3.92
Cell Morphology SMAD3, PRKCD, CDH1, LAMA5, LSP1, DCTN2, VIP, IL18, PTK2, CDK5R1, FN1, KRT8, KRT18, PPARG, TGFBI, E2F1 3.88
Cellular Assembly and Organization APOH, PRKCD, SMAD3, TOP2A, CDH1, DCTN2, EBNA1BP2, NPPB, PTK2, CDK5R1, HCAP-D3, FN1, FGG, KRT8, KRT18, MARK2, LAMC1, PPARG, BNIP3, E2F1 3.88
Carbohydrate Metabolism FN1, B4GALT5, NPPB, PTK2, IL18 3.11
Cellular Movement HOXB2, CCR9, C6, B4GALT5, SMAD3, PRKCD, MGLL, CDH1, LSP1, LAMA5, DCTN2, NPPB, CDK5R1, VIP, PTK2, IL18, FN1, BAG1, ITGAE, PPARG, TGFBI 3.08
Cellular Growth and Proliferation SAT, PRKCD, TXNIP, SMAD3, CDH1, FTH1, LAMA5, SLC30A1, EBNA1BP2, VIP, IL18, PTK2, MLLT3, FGFR2, FN1, PLAC8, BAG1, PRKCQ, BTG1, LAMC1, PPARG, BNIP3, E2F1, SFRP4 3.05
Cell Cycle HCAP-D3, FN1, TXNIP, PRKCD, TOP2A, DCTN2, PPARG, EBNA1BP2, E2F1, VIP 2.57
Molecular Transport FGFR2, SAT, FN1, PRKCD, MGLL, BAG1, FTH1, PPARG, NPPB, PTK2, VIP, IL18 2.45
Nucleic Acid Metabolism SAT, BAG1, NPPB, VIP 2.45
Small Molecule Biochemistry APOH, SAT, PRKCD, B4GALT5, MGLL, FTH1, ASAH1, NPPB, PTK2, IL18, VIP, ASS, GLRX, FGFR2, FN1, BAG1, PPARG 2.45
Cellular Function and Maintenance CCR9, SMAD3, CDH1, SLC30A1, PTK2, IL18, CDK5R1, FN1, FGG, KRT18, ITGAE, PPARG, BNIP3 2.25
DNA Replication, Recombination, and Repair HCAP-D3, FN1, SMAD3, PRKCD, TOP2A, FTH1, DCTN2, EBNA1BP2 2.17
Gene Expression APOH, SMAD3, PRKCD, CDH1, PKN2, VIP, IL18, FN1, BAG1, PRKCQ, RNF4, PPARG, E2F1 2.13
Cell Signaling ASS, FN1, PRKCD, PPARG 2.02
Amino Acid Metabolism ASS, FTH1 1.94
Cellular Compromise PRKCD, KRT18, TIMM8A, PPARG, E2F1 1.94
Drug Metabolism GLRX, FTH1, NPPB, IL18, VIP 1.94
Lipid Metabolism FGFR2, APOH, SAT, FN1, MGLL, ASAH1, PPARG, NPPB, VIP 1.94
Post-Translational Modification PRKCD, BAG1, PRKCQ 1.94
Protein Folding BAG1 1.94
Protein Synthesis BAG1, IL18 1.94
Vitamin and Mineral Metabolism FGFR2, FTH1, PPARG 1.94