|
miR-15a
|
Decreased expression in chronic lymphocytic leukaemia
|
Bcl-2
|
|
miR-16
|
Binds to UA rich elements in 3' UTR and induces TNF alpha mRNA degradation
|
TNFα
|
|
miR-21
|
Increased expression in B-cell lymphoma and chronic lymphocytic leukaemia
| |
|
miR-17-5p
|
Inhibits monocyte proliferation, differentiation and maturation
|
AML-1
|
|
miR-20a
|
Inhibits monocyte proliferation, differentiation and maturation
|
AML-1
|
|
miR-106a
|
Inhibits monocyte proliferation, differentiation and maturation
|
AML-1
|
|
miR-24
|
Inhibits replication of vesicular stomatitis virus
| |
|
miR-29a
|
Down-regulated in B-cell chronic lymphocytic leukemia
|
Tcl-1
|
|
miR-122
|
Required for hepatitis C proliferation in liver
| |
|
miR-125b
|
Expression downregulated by LPS and oscillations in expression after exposure to TNF alpha
|
TNFα
|
|
miR-146a
|
Expression induced in macropahges and epithilial following activation of TLR or exposure to TNF alpha and IL-1beta
|
IRAK1, TRAF6
|
|
miR-146b
|
LPS induced expression induced in macrophages
|
IRAK1, TRAF6
|
|
let-7i
|
Regulates TLR-4 and contributes to cholangiocyte immune responses
| |
|
miR-181a
|
Positive regulator of B-cell development and CD4+ T-cell selection, activation and sensitivity
|
SHP-2, PTPN22, DUSP5, DUSP6
|
