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Table 9 miRNAs involvement in immune response [11]

From: Identification of differentially expressed miRNAs in chicken lung and trachea with avian influenza virus infection by a deep sequencing approach

miRNA Functions Targets
miR-15a Decreased expression in chronic lymphocytic leukaemia Bcl-2
miR-16 Binds to UA rich elements in 3' UTR and induces TNF alpha mRNA degradation TNFα
miR-21 Increased expression in B-cell lymphoma and chronic lymphocytic leukaemia  
miR-17-5p Inhibits monocyte proliferation, differentiation and maturation AML-1
miR-20a Inhibits monocyte proliferation, differentiation and maturation AML-1
miR-106a Inhibits monocyte proliferation, differentiation and maturation AML-1
miR-24 Inhibits replication of vesicular stomatitis virus  
miR-29a Down-regulated in B-cell chronic lymphocytic leukemia Tcl-1
miR-122 Required for hepatitis C proliferation in liver  
miR-125b Expression downregulated by LPS and oscillations in expression after exposure to TNF alpha TNFα
miR-146a Expression induced in macropahges and epithilial following activation of TLR or exposure to TNF alpha and IL-1beta IRAK1, TRAF6
miR-146b LPS induced expression induced in macrophages IRAK1, TRAF6
let-7i Regulates TLR-4 and contributes to cholangiocyte immune responses  
miR-181a Positive regulator of B-cell development and CD4+ T-cell selection, activation and sensitivity SHP-2, PTPN22, DUSP5, DUSP6