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Table 3 Age-regulated co-expression modules

From: Genes and gene expression modules associated with caloric restriction and aging in the laboratory mouse

Modules

M (P-Value)

Minimal |r|

{Nckap1l, Evi2a}

10.2 (0.101)

0.946

{Plek, Ncf1}

9.96 (0.208)

0.908

{Sfi1, 4933439C20Rik}

9.93 (0.235)

0.780

{Psmb8, Psmb9, H2-K1}

10.0 (< 0.001)

0.859

{Tyrobp, Mpeg1, Ctss}

9.87 (< 0.001)

0.863

{Sfi1, Pisd, 4933439C20Rik}

9.85 (< 0.001)

0.599

{Tyrobp, Mpeg1, Fcgr3, Fcer1g, Plek}

9.85 (< 0.001)

0.821

{Psmb8, Psmb9, H2-M3, H2-K1, Tap2}

9.29 (< 0.001)

0.813

{Evi2a, Ly86, Pkib, March1, Lair1}

9.16 (< 0.001)

0.713

  1. The table lists the most significant age-regulated co-expression modules containing 2, 3, or 5 genes. Values in this table are interpreted in the same way as those listed in Table 2, except here the M statistic reflects responsiveness of a module to aging (rather than CR). Additional File 11 provides a more detailed description of these and other co-expression modules that emerged as significantly associated with aging.