Genome-wide nucleosome mapping of Plasmodium falciparum reveals histone-rich coding and histone-poor intergenic regions and chromatin remodeling of core and subtelomeric genes

Table 1 Mean nucleosome enrichment values and Pearson correlation of nucleosome patterns between different stages.

		Mean Log₂ ratio of probes ≤10				Pearson Correlation Coefficient
		Change	Ring	Trophozoite	Schizont	Ring vs Trophozoite	Ring vs Schizont	Trophozoite vs Schizont
Whole Genome	All Probes	0.14	-0.14	0.00	-0.12	0.70	0.89	0.57
	Coding	0.21	0.10	0.24	0.04	0.70	0.85	0.56
	Non-coding	0.20	-0.62	-0.50	-0.42	0.70	0.93	0.59
Core Regions	All Probes	0.19	-0.11	-0.01	-0.20	0.71	0.89	0.55
	Coding	0.22	0.13	0.22	0.00	0.72	0.85	0.55
	Non-coding	0.13	-0.76	-0.62	-0.73	0.69	0.93	0.55
Sub-telomere	All Probes	0.46	-0.40	0.01	0.06	0.69	0.93	0.60
	Coding	0.65	-0.19	0.46	0.34	0.64	0.89	0.54
	Non-coding	0.40	-0.56	-0.34	-0.17	0.71	0.94	0.63
Internal var clusters	All Probes	0.77	-0.50	0.27	0.23	0.67	0.93	0.60
	Coding	1.03	-0.37	0.66	0.51	0.59	0.93	0.49
	Non-coding	0.61	-0.62	-0.08	-0.01	0.72	0.94	0.67
Telomere	All Probes	1.50	0.43	-0.05	1.45	0.63	0.93	0.52

ISSN: 1471-2164