Figure 5

External validation of the predicted binding sites using binding motifs. The significance of the overlap of the identified peaks with the corresponding high-scoring sequence motifs (see Table 2 for the motif identifiers) was assessed by the Genomatix RegionMiner software separately for each transcription factor (columns), either when using all the detected peaks (upper panel) or when focusing on the top 1000 peaks only (lower panel). The medians over the ChIP samples (bars) are shown together with the minimum and maximum values (error bars).