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Figure 1 | BMC Genomics

Figure 1

From: Functional diversity of human protein kinase splice variants marks significant expansion of human kinome

Figure 1

Cartoon representation of domain organization of newly recognized splice variants encoded by a single gene which have different domain organization. Splice variants shown in the figure are closely related to a) MARK kinase; b) CAMK II subfamily; c) Fyn tyrosine kinase d) Trio kinase. Abbreviations followed in the figure: UBA, Ubiquitin Associated Domain; KA1, Kinase Associated Domain 1; CAMKII_AD, Calcium/calmodulin dependent protein kinase II Association; SH3, Src homology 3; SH2, Src homology 2; I-set, Immunoglobulin domain; RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; PH, Pleckstrin Homology domain.

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BMC Genomics

ISSN: 1471-2164

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