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Table 1 Lowest EASE Scores in Canine Osteosarcoma and Associated Functions.

From: Canine tumor cross-species genomics uncovers targets linked to osteosarcoma progression

GO FUNCTION

CATEGORY

LH2

EASE SCORE1

FISHER EXACT

Cellular Component

ECM

33

5.7E-11

1.09E-12

Molecular Function

ECM structural

16

9.56E-10

8.07E-11

Molecular function

Structural molecule activity

40

0.00000319

0.000013

Molecular function

Ca ion binding

30

0.000132

0.0000565

Cellular component

Extracellular

49

0.000192

0.000105

Biological process

Development

60

0.000227

0.000135

Cellular component

ER

32

0.000285

0.000131

Molecular function

Protein binding

72

0.00403

0.000261

Biological process

Morphogenesis

41

0.000431

0.000228

Biological process

ER to Golgi transport

6

0.00476

0.0000344

Cellular component

Actin cytoskelton

17

0.00354

0.00141

  1. 1 Categories with significant Expression Analysis Systematic Explorer (EASE) scores (<0.001) are presented here.
  2. 2 LH represents number of genes in gene list assigned to a category.
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BMC Genomics

ISSN: 1471-2164

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