Figure 1

Mapping of sequences relative to probe position in the genome. a) Sequence coverage distribution averaged across all targeted regions captured by basal capture protocol and b) sequence coverage distribution averaged across all targeted regions captured by double hybridization (modified) protocol show that the sequence reads are tightly limited around the targeted regions. Here, a targeted region is not necessarily a targeted exon but a probeset composed of multiple probes that are < 200 bp apart to each other. The y axis plots the relative abundance and the x axis is the base position relative to the probes positions.