Figure 2
From: Differential gene expression in ADAM10 and mutant ADAM10 transgenic mice
Venn diagrams with SAM-based gene lists of mono- and double-transgenic mice. Venn diagram I (ADAM10 versus FVB/N (A) is compared with ADAM10/APP[V717I] versus APP[V717I] (B)), and Venn diagram II (dnADAM10 versus FVB/N (A) is compared with dnADAM10/APP[V717I] versus APP[V717I] (B)), generated by a custom-written Perl-script, show the effects of the overexpression of ADAM10 and dnADAM10 in mono- and double-transgenic mice. The numbers in the space of overlapping circles represent the number of transcripts that were affected in both mouse lines.