Figure 9
From: Differential gene expression in ADAM10 and mutant ADAM10 transgenic mice
Analyses of gene expression of selected candidate genes by real-time RT-PCR in double-transgenic mice. Expression levels of individual genes in double-transgenic mice in relation to gene expression in APP[V717I] mono-transgenic mice. Shown are the results from RT-PCR and microarray analyses. Values presented: mean of fold changes ± SD of 4–6 animals. A: ADAM10; B: Vldlr; C: Gria1; D: Gria2; E: Mapt; F: Nlgn1. Statistical significance was determined by using ANOVA analysis, followed by Dunnett's post hoc comparison (*), p ≤ 0.05; (**), p ≤ 0.001; (***), p ≤ 0.001.