Table 3 Numbers of significantly regulated genes in double-transgenic mice (5 months, 3 females and 3 males per group) restricted by the given d-values.
From: Differential gene expression in ADAM10 and mutant ADAM10 transgenic mice
Mouse Genome 430 2.0 Array (Affymetrix) | |||
|---|---|---|---|
45 000 probe sets, 39 000 transcripts, 34 000 characterized | |||
ADAM10/APP[V717I] versus APP[V717I] 592 genes, FDR = 0.0% | dnADAM10/APP[V717I] versus APP[V717I] 600 genes, FDR = 0.0% | ||
295 upregulated (d-value > 2.06) | 297 downregulated (d-value < -1.56) | 300 upregulated (d-value > 3.29) | 300 downregulated (d-value < -2.85) |