Impact of breed and sex on porcine endocrine transcriptome: a bayesian biometrical analysis

BMC Genomics

Table 6 Over represented Gene Ontology (GO) categories in modules with largest discrepancy between observed and expected number of probesets

Tissue	Module	n_OBS	n_EXP	GO Name	P-value	FDR
Male Gonad	4	47	5	Spermatogenesis	10^-5	0.05
				Spermatid development	0.002	0.37
				Spindle organization	0.002	0.07
	14	13	2	Muscle cell differentiation	10^-5	0.07
				Mitotic sister chromatid cohesion	10^-4	0.32
				Negative regulation of transcription	0.003	0.77
	29	12	2	Aldehide metabolic process	0.003	0.34
				RNA metabolic process	0.006	0.34
				Glycogen metabolic process	0.007	0.34
Backfat	25	34	1	Striated muscle contraction	< 10^-5	10^-4
				Regulation of striated m. contraction	10^-4	0.03
				Ventricular cardiac muscle morphogenesis	0.001	0.30

Module: The number of probesets per module is shown in Figure 2
n_OBS: Number of probesets, among those with 100 highest SD_zbreed, observed in the module
n_EXP: Number of probesets expected in the module
FDR: false discovery rate

ISSN: 1471-2164