Table 1 List of gene set regulated by IL-6 in PC12 cells

Cytokines

   chemokine ligand 13

   chemokine ligand 10

Enzymes

   cytochrome P450, 4f16

   ceruloplasmin

   peptidyl arginine deiminase, type III

   acyl-CoA synthetase, member 1

   transglutaminase 1

   nitric oxide synthase 2A

   ornithine carbamoyltransferase

   Similar to Lysophospholipase

   trehalase

   kynureninase

   nitric oxide synthase 3

   glycine amidinotransferase

   guanine nucleotide binding protein, alpha z

   ST6 galactosamide alpha-2,6-sialyltranferase 1

   aldo-keto reductase, 1C1

   myxovirus resistance 1

   aldolase C

   2',5'-oligoadenylate synthetase 1

   protein disulfide isomerise, A2

   RNA (guanine-7-) methyltransferase

   polymerase, alpha 2

   steroid-5-alpha-reductase, alpha 1

   aminolevulinate, delta-, synthase 2

   glutathione S-transferase A3

   UDP glycosyltransferase 8

   cell division cycle 42

   cysteine dioxygenase, type I

   ST8 alpha-2,8-sialyltransferase 3

G-protein coupled receptors

   adrenergic receptor, alpha-2B

   arginine vasopressin receptor 2

   vasoactive intestinal peptide receptor 1

   cholinergic receptor, muscarinic 3

   cholinergic receptor, muscarinic 4

Growth factors

   regenerating islet-derived 3 alpha

   regenerating islet-derived 3 beta

   growth differentiation factor 15

   platelet-derived growth factor alpha

   nudix-type motif 6

   jagged 2

   hepatocyte growth factor

   macrophage stimulating 1

Ion channels

   glutamate receptor, ionotropic, delta 2

   purinergic receptor P2X

Kinases

   fyn-related kinase

   Janus kinase 2

   phosphatidylinositol 4-kinase beta

   pim-3 oncogene

   fer tyrosine kinase

   mitogen-activated protein kinase kinase 5

   fibroblast growth factor receptor 1

   activin receptor, type IIA

Nuclear receptors

   retinoic acid receptor alpha

   nuclear receptor, *C2

   vitamin D receptor

Peptidases

   complement component 1s

   caspase 1

   proteasome subunit, alpha 1

   kallikrein-related peptidase 8

Phosphatases

   pyruvate dehydrogenase phosphatase 2

   protein tyrosine phosphatase receptor D

Transcription regulators

   signal transducer and activator of transcription 1

   Kruppel-like factor 6

   HIV-1 Tat interacting protein

   HIV enhancer binding protein 2

   upstream transcription factor 1

   early growth response 1

   interferon regulatory factor 1

   signal transducer and activator of transcription 2

   breast cancer 1

   D site of albumin promoter binding protein

   nuclear factor I/B

   transcription elongation factor A 2

Transmembrane receptors

   oxidized low density lipoprotein receptor 1

   histocompatibility 2, Q region locus 10

   insulin-like growth factor 2 receptor

   Fc fragment of IgG receptor IIa (CD32)

   growth hormone receptor

Transporters

   cadherin 17

   solute carrier family 6, member 3

   nucleoporin 153kDa

   solute carrier family 9, member 2

   cadherin 17

   lipocalin 2

   syntaxin 4

   secretory carrier membrane protein 2

   solute carrier family 12, member 5

   solute carrier family 30, member 2

   syntaxin 5

Others

   regenerating islet-derived 1 alpha

   TIMP metallopeptidase inhibitor 1

   calcitonin-related polypeptide beta

   fibrinogen gamma chain

   trans-golgi network protein 2

   LIM and senescent cell antigen-like domains 1

   alpha-2-HS-glycoprotein

   ribosomal protein L3-like

   collagen, type IV, alpha 5

   parvalbumin

   YTH domain containing 1

   growth hormone releasing hormone

   annexin A1

   collagen, type XII, alpha 1

   regenerating islet-derived 3 gamma

   adenylate cyclase activating polypeptide 1

   heat shock protein 90 kDa, alpha B 1

   luteinizing hormone beta

   galectin 5

   myocilin

   prolactin family 8a81

   troponin C type 2

   ribosomal protein L18a

   fibrinogen beta chain

   tropomyosin 3

   tubulin, beta

   extracellular proteinase inhibitor

   growth associated protein 43

   galectin 9

   tubulin, alpha 4a

   BCL2-like 11

   integrin alpha 7

   syndecan 2

   zinc finger protein 260

   filamin C

   metallothionein 3

   arginine vasopressin

   fasciculation and elongation protein zeta 1

   crystallin, alpha B

   neurofascin