Table 2 List of gene set regulated by NGF in PC12 cells

Enzymes

   rat senescence marker protein 2A gene

   myosin, heavy chain 3

   lecithin-cholesterol acyltransferase

   UDP glucuronosyltransferase 2, polypeptide A1

   contactin 4

   phosphodiesterase 4B,

   gulonolactone (L-) oxidase

   superoxide dismutase 3

   fibronectin 1

   acetylcholinesterase

   tryptophan hydroxylase 1

   aldo-keto reductase family 1, member C1

   guanine nucleotide binding protein, alpha z

   aminoadipate aminotransferase

   phospholipase D2

   N-deacetylase/N-sulfotransferase 1

   phosphate cytidylyltransferase 2

   peptidylprolyl isomerase A

   Rab geranylgeranyltransferase alpha

   glutathione S-transferase A3

   cytochrome P450, 4F4

   3-hydroxyanthranilate 3,4-dioxygenase

   stearoyl-Coenzyme A desaturase 2

   aldo-keto reductase family 1, member C3

   myxovirus resistance 2

   serine dehydratase

G-protein coupled receptors

   calcitonin/calcitonin-related polypeptide alpha

   angiotensin II receptor 1

   cholinergic receptor, muscarinic 3

   parathyroid hormone receptor 1

Growth factors

   growth differentiation factor 15

   transforming growth factor beta 1

   brain-derived neurotrophic factor

   neuregulin 1

Ion channels

   calcium channel, voltage-dependent, beta 2

   glutamate receptor, ionotropic, delta 2

   sodium channel, voltage-gated, type II, beta

   potassium inwardly-rectifying channel J4

   solute carrier family 9 member 3

   purinergic receptor P2X, ligand-gated ion channel 2

   sodium channel, voltage-gated, type I, alpha

   purinergic receptor P2X-like 1

   gamma-aminobutyric acid A receptor gamma 2

Kinases

   G protein-coupled receptor kinase 5

   protein kinase, cGMP-dependent, type II

   mitogen-activated protein kinase kinase kinase kinase 1

   calcium/calmodulin-dependent serine protein kinase

   discs, large homolog 1

   phosphatidylinositol 4-kinase beta

   discoidin domain receptor family member 1

   non-metastatic cells 6

Peptidases

   carboxypeptidase A3

   ADAM metallopeptidase domain 17

   Proteasome subunit alpha 1

   protein disulfide isomerase family A member 3

   caspase 1

Phosphatases

   dual specificity phosphatase 6

   protein phosphatase 1 subunit 1A

   protein tyrosine phosphataser type 11

Transcription regulators

   jun dimerization protein 2

   cAMP responsive element modulator

Transmembrane receptors

   cholinergic receptor, nicotinic, beta 1

Transporters

   solute carrier family 1 member 1

   solute carrier family 22, member 3

   gap junction protein, beta 2

   solute carrier family 1, member 3

   solute carrier family 22, member 6

   vacuolar protein sorting 33 homolog B

   solute carrier family 30, member 1

   syntaxin 4

   murinoglobulin 1

   ATPase, Cu++ transporting, beta polypeptide

Others

   BCL2/adenovirus E1B interacting protein 3

   natriuretic peptide precursor C

   trans-golgi network protein 2

   fibrillin 2

   amyloid P component, serum

   zinc finger, matrin type 3

   LIM and senescent cell antigen-like domains 1

   CD44 molecule

   common salivary protein 1

   selectin P

   collagen, type XI, alpha 1

   collagen, type XII, alpha 1

   nucleosome assembly protein 1-like 4

   spermine binding protein

   ribosomal protein L35

   connector enhancer of kinase suppressor of Ras 2

   prolactin family 8, subfamily a, member 81

   extracellular proteinase inhibitor

   fibrinogen gamma chain

   smooth muscle alpha-actin

   tropomyosin 1 alpha

   calcineurin binding protein 1

   crystallin, gamma E

   follistatin-like 1

   secreted phosphoprotein 2

   tachykinin, precursor 1

   myosin light chain 9

   ubiquitin B

   golgin B1 protein

   lysosomal-associated membrane protein 1