Global gene expression analysis reveals reduced abundance of putative microRNA targets in human prostate tumours

BMC Genomics

Table 2 Biological processes of down-regulated miRNA targets and antitargets in prostate cancer

		Targets (1296)		AntiTargets (1293)
GO Term	Biological Process	mRNAs	P (over)^†	mRNAs	P (over)^†
GO:0009987	Cellular process	1000	1.E-47	874	1.E-11
GO:0008152	Metabolic process	627	2.E-04	627	2.E-04
GO:0043170	Macromolecule metabolic process	545	4.E-12	473	2.E-02
GO:0050789	Regulation of biological process	494	7.E-67	317	2.E-08
GO:0007154	Cell communication	405	2.E-39	254	2.E-02
GO:0007275	Multicellular organismal development	302	4.E-83	180	4.E-19
GO:0030154	Cell differentiation	202	4.E-43	133	4.E-12
GO:0008219	Cell death	107	4.E-24	67	4.E-06

^†: Over-represent P value was calculated using Hyper-Geometric (HG) distribution and adjusted. P values < 1E-20 (for mRNAs overrepresentation in each category) are in bold.

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