Table 1 Simple RNAi system equations
From: Comparing 2-nt 3' overhangs against blunt-ended siRNAs: a systems biology based study
| Reaction | Rate Constant | |
|---|---|---|
| 1 | mRNA + siRNA -> gRNA | 0.008 hr-1 |
| 2 | dsRNA -> 10*siRNA | 2.0 hr-1 |
| 3 | mRNA -> dsRNA | 0.002 hr-1 |
| 4 | ϕ-> mRNA | 160.0 hr-1 |
| 5 | siRNA ->ϕ | 2.0 hr-1 |
| 6 | mRNA ->ϕ | 0.14 hr-1 |
| 7 | gRNA ->ϕ | 2.8 hr-1 |