Figure 3

Summary of significant changes in P. multocida gene expression grouped by COGs. Numbers on the y-axis represent the percentage of genes in each COG category whose expression either significantly increased (black bars) or decreased (gray bars) in response to antibiotic treatment. COG category descriptions are: A, RNA processing and modification; K, Transcription; L, Replication, recombination and repair; D, Cell cycle control, mitosis and meiosis; V, Defense mechanisms; T, Signal transduction mechanisms; M, Cell wall/membrane biogenesis; N, Cell motility; W, Extracellular structures; U, Intracellular trafficking and secretion; O, Posttranslational modification, protein turnover, chaperones; C, Energy production and conversion; G, Carbohydrate transport and metabolism; E, Amino acid transport and metabolism; F, Nucleotide transport and metabolism; H, Coenzyme transport and metabolism; I, Lipid transport and metabolism P, Inorganic ion transport and metabolism; Q, Secondary metabolites biosynthesis, transport and catabolism R, General function prediction only; S, Function unknown; -, not in COGs