Table 1 List of the proteins with high strength scores in the human 'aging network'.
Genes | Common Names | Function | Score |
|---|---|---|---|
GRB2 | Growth factor receptor-bound protein 2 | SH3/SH2 adaptor activity | 75.76 |
NCK1 | Cytoplasmic protein NCK1 | Receptor binding | 61.24 |
ABL1 | Proto-oncogene tyrosine-protein kinase ABL1 | ATP binding | 46.16 |
TP53 | Cellular tumour antigen p53 | Apoptosis | 45.97 |
E1 | Replication protein E1 | ATP binding | 42.05 |
YWHAZ | 14-3-3 protein zeta/delta | Anti-apoptosis | 37.83 |
KIAA1377 | Uncharacterized protein KIAA1377 | Protein binding | 36.87 |
EEF1A1 | Elongation factor 1-alpha 1 | Protein binding | 36.45 |
UNC119 | Protein unc-119 homolog A | Synaptic transmission | 33.69 |
HSPA8 | Heat shock cognate 71 kDa protein | ATP binding | 33.08 |