Figure 1
From: Increased incidence of rare codon clusters at 5' and 3' gene termini: implications for function
Effects of synonymous codon substitutions on %MinMax. The %MinMax calculation was applied to a series of synonymous sequences encoding the N-terminal 18 amino acids of Salmonella phage P22 tailspike. The first 18 codons of the wild type tailspike mRNA sequence (middle line) can be changed to common codons (bold text) or rare codons (gray text), resulting in dramatic differences in the %MinMax output, without altering the underlying amino acid sequence.