Figure 2

Genomic organization of the znr - zur gene region in corynebacterial genomes and M. tuberculosis H37Rv. (A), Comparison of the znr-zur genome region. The respective gene regions were obtained from C. glutamicum ATCC 13032 (NC_006958), C. efficiens YS-314 (NC_004369), C. diphtheriae NCTC 13239 (NC_002935), C. aurimucosum DSM44827 (NC_012590), C. accolens ATCC 49725 (NZ_ACGD00000000), C. urealyticum DSM7109 (NC_010545), C. jeikeium K411 (NC_007164), C. kroppenstedtii DSM44385 (NC_012704), and M. tuberculosis H37Rv (NC_000962). Orthologous genes are specifically labeled. Please note that the gene regions of C. jeikeium and C. accolens are shown in reversed orientation. (B), The znr upstream region of C. glutamicum ATCC 13032. The mapped transcription start site (+1) and the deduced core promoter regions (- 35 and - 10) are marked in bold. A stretch of six thymine residues representing a potential up-element is boxed. A putative ribosome-binding site (RBS) is indicated, the GTG start codon of znr is underlined.