Figure 2

Topology diagrams of Candida antarctica lipase A, Bacillus subtilis deacetylase and Candida rugosa lipase. The shared cap region between C. antarctica lipase A and B. subtilis deacetylase is colored orange. The additional 3 α-helices of the cap region in CALA are labelled D₃, D₄ and D₅ and colored in dark green. The C-terminal, presumably lid forming β-strands of CALA are labelled 9 and 10. The lid forming α-helix of C. rugosa lipase is labelled A_-1. PDB identifiers for the structures are 2VEO (Candida antarctica lipase A), 1L7A (Bacillus subtilis deacetylase), and 1CRL (Candida rugosa lipase).