Table 1 Functions of selected genes deleted in CTBT sensitive mutant strains
Function | Gene (ORF) name |
|---|---|
Mitochondrial functions | ADH1, AFG3, ATP1, ATP11, ATP12, ATP18, CIT1, CYT1, DIA4, IMP1, ISA1, ISA2, MAS37, MDM32, MDM38, MGM1, MIP1, MRPL49, MRPS35, MRS1, MSY1, MTG1, OCT1, PCP1, PDC1, PHB1, RML2, RSM19, SOD1, SOD2, TUF1, YDR115W, YGL085W |
Chromatin remodeling and transcription | ARP5, CDC73, CTK1, HOS2, HPR1, IES6, MED2, MGA2, OPI1, PGD1, RRN10, RME1, ROX3, RSC1, RTF1, RTT109, SGF73, SKN7, SNF2, SPT4, SPT20, SRB5, STP1, SWI3, SWI4, TAF14, THO2, UME6, YAF9, YAP1, YAP7 |
DNA repair | MET18, MMS1, MMS4, MRE11, RAD6, RAD18, RAD50, RAD51, RAD54, RAD57, XRS2 |
Lipid metabolism | AKR1, CHO1, CHO2, DAP1, ERG2, ERG3, ERG6, ERG24, MGA2, OPI1 |
Stress response and signal transduction | ASC1, BCK1, CCS1, CTR1, CYS3, NBP2, REG1, SKN7, SNF1, SOD1, SOD2, YAP1, YAP7 |
Vacuolar functions | AVT4, CWH36, KCS1, TFP1, TFP3, VMA4, VMA21, VMA22 |
Protein sorting and degradation | DIA2, MAP1, PRE9, RAD6, VPS15, VPS20, VPS34 |
Amino acid metabolism | CYS3, ILV1, PRO2, TRP2, TRP3, TRP5 |
Transport | AVT4, CTR1, MUP1, TAT1 |
Mannosyl transferases | ANP1, OCH1 |
Pentose phosphate pathway | GND1, RPE1 |
Ungrouped | ARD1, BEM1, BIM1, BUB3, BUD25, BUD27, BUR2, CDC50, CIK1, CSM1, CTF18, ENV6, FYV10, GEP4, GET2, HTZ1, KRE28, MTC5, NAT1, NAT3, NCE101, NPT1, NRP1, NUP133, ORM2, PHO85, RAI1, RCY1, REF2, RGI1, RNR4, RPL1B, RPL2A, RPL42B, RTC1, SBH1, YIM2 |
Unknown functions | YDR049W, YDR114C, YHR045W, YNR065C, YOR305W |