Skip to main content

Table 1 Functions of selected genes deleted in CTBT sensitive mutant strains

From: Chemogenomic and transcriptome analysis identifies mode of action of the chemosensitizing agent CTBT (7-chlorotetrazolo[5,1-c]benzo[1,2,4]triazine)

Function Gene (ORF) name
Mitochondrial functions ADH1, AFG3, ATP1, ATP11, ATP12, ATP18, CIT1, CYT1, DIA4, IMP1, ISA1, ISA2, MAS37, MDM32, MDM38, MGM1, MIP1, MRPL49, MRPS35, MRS1, MSY1, MTG1, OCT1, PCP1, PDC1, PHB1, RML2, RSM19, SOD1, SOD2, TUF1, YDR115W, YGL085W
Chromatin remodeling and transcription ARP5, CDC73, CTK1, HOS2, HPR1, IES6, MED2, MGA2, OPI1, PGD1, RRN10, RME1, ROX3, RSC1, RTF1, RTT109, SGF73, SKN7, SNF2, SPT4, SPT20, SRB5, STP1, SWI3, SWI4, TAF14, THO2, UME6, YAF9, YAP1, YAP7
DNA repair MET18, MMS1, MMS4, MRE11, RAD6, RAD18, RAD50, RAD51, RAD54, RAD57, XRS2
Lipid metabolism AKR1, CHO1, CHO2, DAP1, ERG2, ERG3, ERG6, ERG24, MGA2, OPI1
Stress response and signal transduction ASC1, BCK1, CCS1, CTR1, CYS3, NBP2, REG1, SKN7, SNF1, SOD1, SOD2, YAP1, YAP7
Vacuolar functions AVT4, CWH36, KCS1, TFP1, TFP3, VMA4, VMA21, VMA22
Protein sorting and degradation DIA2, MAP1, PRE9, RAD6, VPS15, VPS20, VPS34
Amino acid metabolism CYS3, ILV1, PRO2, TRP2, TRP3, TRP5
Transport AVT4, CTR1, MUP1, TAT1
Mannosyl transferases ANP1, OCH1
Pentose phosphate pathway GND1, RPE1
Ungrouped ARD1, BEM1, BIM1, BUB3, BUD25, BUD27, BUR2, CDC50, CIK1, CSM1, CTF18, ENV6, FYV10, GEP4, GET2, HTZ1, KRE28, MTC5, NAT1, NAT3, NCE101, NPT1, NRP1, NUP133, ORM2, PHO85, RAI1, RCY1, REF2, RGI1, RNR4, RPL1B, RPL2A, RPL42B, RTC1, SBH1, YIM2
Unknown functions YDR049W, YDR114C, YHR045W, YNR065C, YOR305W