Table 1 General features of the H. mustelae genome, and those of selected Campylobacterales
Species | Helicobacter mustelae | Helicobacter pylori | Helicobacter acinonychis | Helicobacter hepaticus | Campylobacter jejuni | Wolinella succinogenes | |
|---|---|---|---|---|---|---|---|
Strain | ATCC43772†12198 | 26695 [28] | J99 [27] | Sheeba [30] | ATCC 51449 [29] | NCTC 11168 [31] | DSM 1740 [34] |
Host(s) | Ferrets | Human | Human | Large felines | Rodent | Human & avian | Bovine |
Genome size (bp) | 1,578,097 | 1,667,867 | 1,643,831 | 1,553,928 | 1,799,146 | 1,641,481 | 2,110,355 |
GC content (%) | 42.47 | 39.0 | 39.0 | 38.2 | 35.9 | 30.6 | 48.5 |
Predicted ORFs | 1,403†| 1,590 (1,552 [143]) | 1,495 | 1,611 | 1,875 | 1,654 | 2,046 |
Coding area (%) | 91.9% | 91.0 | 90.8 | 89.7 | 93.0 | 94.3 | 93.0 |
Av.gene length (bp) | 995 | 945 | 998 | 865 | 1,082 | 948 | 964 |
Plasmids | None | None* | None* | One | None | None§ | None |
Phages and phage-like elements | 4 phage genes | None | None | 41 phage genes in two prophage | 3 phage genes | None | Prophage-tRNAmet |
IS elements | None | IS605, IS606 | IS605 (partial), IS606 | ISHa1675 | None | Cj0752 (partial) | ISWsu1302, ISWsu1203 |
Genomic islands | None | cag PAI | cag PAI | HAcG1 integron | HHGI1 | None | WsuGI I and II |
Regions of deviating GC content | Autotransporter genes, flagellin modification, surface proteins | Genomic islets & islands, DNA-restriction/modification system, translation machinery | Genomic islets & islands, DNA-restriction/modification system, translation machinery | Hypotheticals and plasmid-related genes | Genomic islets & islands, DNA-restriction/modification system, translation machinery | EPS/LOS synthesis & flagella modification | Genomic islets & islands, DNA-restriction/modification system, translation machinery |