Co-expression of neighbouring genes in Arabidopsis: separating chromatin effects from direct interactions

BMC Genomics

Table 3 Overlapping gene pairs on opposing strands

Group		N	Co-expression^a	mRNA abundance^b	P(compared to random pairs)^c
1	3' overlap	948	-0.019	8.39	0.0020
2	5' overlap	23	0.140	7.99	0.142
3	fully contained^d	17	-0.084	7.30	0.103

^aAverage Pearson correlation coefficient
^b average mRNA abundance for all genes is 7.73 (log₂ signal intensity).
^c To derive a Null expectation, we analyzed 100,000 pairs of randomly chosen genes; mean Pearson correlation of this random dataset is 0.014. P-values from Wilcoxon rank sum tests.
^d the shorter gene is fully contained in the longer gene (but transcribed from the opposite DNA strand)

ISSN: 1471-2164