Gcn5 differs in gene regulation and genome-wide localisation in S. cerevisiae and S. pombe during KCl stress adaptation. (A) Gcn5 regulates different sets of KCl responsive genes in S. cerevisiae and S. pombe. The Venn diagram shows the relationship between gene sets identified in S. cerevisiae and S. pombe. (B) The altered Gcn5-myc gene distribution pattern between normal and KCl-stress conditions in S. cerevisiae is not observed in S. pombe. The average gene distribution of Gcn5-myc is shown for genes that are associated with Gcn5 in both the absence and presence of KCl stress. The distribution of Gcn5 is shown for conditions in the absence (blue line) and presence of KCl (red line) for S. cerevisiae (average of 383 genes, upper panel) and S. pombe (average of 504 genes, lower panel), respectively.