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Figure 3 | BMC Genomics

Figure 3

From: Metabolic modeling and analysis of the metabolic switch in Streptomyces coelicolor

Figure 3

Correlation between predicted flux and observed gene expression. The histogram shows the correlation between gene expression and predicted flux for 549 enzyme-coding genes. A large number of enzyme-coding genes show high correlation. They include many primary metabolism genes and antibiotic biosynthesis genes. About half of the genes show poor correlation; these are mostly genes that show constant gene expression and/or predicted flux across the entire time course, leading to a correlation coefficient close to zero. A small but noteworthy number of genes show statistically significant negative correlation between gene expression levels and predicted flux. These cases are discussed in more detail in the main text.

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