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Table 4 TFBS module families with occurences in proximal promoter regions of at least three 8q24.3 ZNF genes

From: The ancient mammalian KRAB zinc finger gene cluster on human chromosome 8q24.3 illustrates principles of C2H2 zinc finger evolution associated with unique expression profiles in human tissues

Module familya

ZNF7

ZNF16

ZNF34

ZNF250

ZNF251

ZNF252

ZNF517

Total

Promoter countb

ETSF_SP1F

2

1

0

2

1

3

2

11

6

EGRF_SP1F

3

0

1

2

2

1

1

10

6

ETSF_ETSF

0

1

1

0

3

1

0

6

4

SP1F_ETSF

1

1

0

1

1

1

1

6

6

IKRS_AP2F

1

0

0

0

1

1

1

4

4

KLFS_SP1F

1

0

0

0

1

1

0

3

3

NFKB_SP1F

0

0

0

1

1

0

1

3

3

SP1F_AP2F

1

0

0

0

0

0

1

3

3

  1. a Modules are functional combinations of (most often 2) TFBS [57]. Subcategories were combined to "module families" for counting. For more detailed lists see Additional file 14
  2. b Number of 8q24.3 ZNF promoter regions with matches of a given TFBS module family
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BMC Genomics

ISSN: 1471-2164

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