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Table 2 Gene Set Enrichment Analysis (GSEA) of transcriptome of mercury-treated human HepG2 cells.

From: Mercury-induced hepatotoxicity in zebrafish: in vivo mechanistic insights from transcriptome analysis, phenotype anchoring and targeted gene expression validation

Enriched processes NES HepG2
Cell cycle 2.2425
Pyrimidine metabolism 2.049
DNA repair 1.6355
DNA damage signaling* 1.4957
Proteasome pathway* 1.5095
Electron transport chain* -1.4248
Nuclear receptor signaling pathway* -1.5093
Mitochondrial fatty acid beta-oxidation* -1.7171
  1. Biological pathways that are statistically enriched with false discovery rate (FDR) < 0.3 or nominal p-value (NP) < 0.1 are considered. * indicate pathways that are common in zebrafish and HepG2 cell treated with HgCl2.