Gene expression profiling during epileptogenesis. (A) Hierarchical clustering of hippocampal genes displaying greater than 2-fold changes in expression following SE (P ≤ 0.05). Each row: relative expression of a single gene; each column: a biological sample; red: hyper-expression; green: hypo-expression. Several genes exhibited a consistent hyper-expression throughout the time points analyzed (black bar cluster) while others were mainly hyper-expressed at D3 (white bar cluster). (B) Venn diagram discriminating the amount of genes differentially expressed three days post-SE (D3), seven days post-SE (D7), and immediately after the first spontaneous seizure (Chronic).