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Figure 2 | BMC Genomics

Figure 2

From: Comparison of clastogen-induced gene expression profiles in wild-type and DNA repair-deficient Rad54/Rad54B cells

Figure 2

Hierarchical clustering of gene expression changes in WT and Rad54/Rad54B MEFs after mutagen or clastogen exposure. Expression changes are given relative to the corresponding control, where red represents up-regulation, green down-regulation and yellow no difference in gene expression levels. The black bar indicates the cluster showing the strongest genotype-dependent effect for the MMC-exposed MEFs. Exposures are as follows: AW: WT MEFs - N-ac-AAF, AR: Rad54/Rad54B MEFs - N-ac-AAF, EW: WT MEFs - ENU, ER: Rad54/Rad54B MEFs - ENU, BW: WT MEFs - BLM, BR: Rad54/Rad54B MEFs - BLM, MW: WT MEFs - MMC, MR: Rad54/Rad54B MEFs - MMC.

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