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Table 4 Representative GO annotations for genes highly diverged in all test species.

From: Using comparative genomic hybridization to survey genomic sequence divergence across species: a proof-of-concept from Drosophila

FBgn

GO_ID

GO_name

Gene_name

%ID Dsec/Dmel

%ID Dsim/Dmel

%ID Dyak/Dmel

FBgn0013300

GO:0003677

DNA binding

Male-specific-transcript-35Ba

81.53

82.76

NoHit

FBgn0033015

GO:0003700

transcription factor activity

d4

NoHit

NoHit

NoHit

FBgn0036496

GO:0003729

mRNA binding

CG7804

89.8

90.52

NoHit

FBgn0039659

GO:0003729

mRNA binding

CG14506

86.81

88.06

81.48

FBgn0000303

GO:0004102

choline O-acetyltransferase activity

Choline acetyltransferase

94.38

96.3

NoHit

FBgn0051742

GO:0004175

endopeptidase activity

CG31742

93.04

92.45

89.66

FBgn0000258*

GO:0004674

protein serine/threonine kinase activity

Casein kinase II alpha subunit

90.53

89.88

87.34

FBgn0020386

GO:0004674

protein serine/threonine kinase activity

Protein kinase 61C

90.62

89.63

NoHit

FBgn0028986

GO:0004867

serine-type endopeptidase inhibitor activity

Serine protease inhibitor 3

93.21

91.91

84.96

FBgn0050289

GO:0004867

serine-type endopeptidase inhibitor activity

CG30289

NoHit

84.64

81.74

FBgn0053225

GO:0004867

serine-type endopeptidase inhibitor activity

CG33225

NoHit

84.18

NoHit

FBgn0040849

GO:0004970

ionotropic glutamate receptor activity

Ionotropic receptor 41a

NoHit

NoHit

NoHit

FBgn0050440*

GO:0005085

guanyl-nucleotide exchange factor activity

CG30440

NoHit

NoHit

NoHit

FBgn0031585

GO:0005200

structural constituent of cytoskeleton

CG2955

92.31

93.85

NoHit

FBgn0028859

GO:0005245

voltage-gated calcium channel activity

CG12455

90.96

90.4

NoHit

FBgn0037885

GO:0005515

protein binding

CG17721

88.99

89.57

NoHit

FBgn0050054

GO:0005525

GTP binding

CG30054

89.71

89.71

NoHit

FBgn0040099

GO:0005534

galactose binding

lectin-28C

87.32

87.32

82.99

FBgn0026175

GO:0006511

ubiquitin-dependent protein catabolic process

skpC

87.57

85.24

85.27

FBgn0058006*

GO:0007155

cell adhesion

CG40006

85.07

79.59

86.17

FBgn0052547

GO:0007186

G-protein coupled receptor protein signaling

CG32547

94.83

94.83

NoHit

FBgn0003373*

GO:0007594

puparial adhesion

Salivary gland secretion 3

84.15

NoHit

NoHit

FBgn0030420

GO:0008234

cysteine-type peptidase activity

CG12717

NoHit

NoHit

81.82

FBgn0031208

GO:0008234

cysteine-type peptidase activity

CG11023

83.67

83.95

83.33

FBgn0029661

GO:0008270

zinc ion binding

CG16781

NoHit

86.86

NoHit

FBgn0039498

GO:0008270

zinc ion binding

CG17991

85.2

84.31

82.4

FBgn0038005

GO:0009055

electron carrier activity

Cyp313a5

NoHit

NoHit

89.6

FBgn0013576

GO:0016998

cell wall catabolic process

l(3)82Fd

92.65

94.12

NoHit

FBgn0002855

GO:0018991

oviposition

Accessory gland-specific peptide 26Aa

84.21

83.45

NoHit

  1. GO category shown for each gene was selected based on informational content and preponderance of evidence for that GO annotation. Genes not annotated beyond the terms molecular function, biological process, or cellular component, are not included. NoHit: no BLAST hit of array feature sequence to heterologous genome sequence (e-value < 10-14). *represented by multiple array features
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BMC Genomics

ISSN: 1471-2164

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