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Table 1 Gene families encoding glycolytic enzymes and the parent genes that are retroposed.

From: Frequent and recent retrotransposition of orthologous genes plays a role in the evolution of sperm glycolytic enzymes

 

Human

Mouse

Gene Family

Gene Name

Position

Ret.seq.

Gene Name

Position

Ret.seq.

Hexokinase

HK1

10:71

No

Hk1

10:62

Yes (1)

 

HK2

02:75

Yes (1)

Hk2

6:83

No

 

HK3

05:176

No

Hk3

13:55

No

 

GCK

07:44

No

Gck

11:6

No

 

HKDC1

10:71

No

Hkdc1

10:62

No

Glucose Phosphate Isomerase

GPI1

19:40

Yes (1)

Gpi1

7:34

Yes (1)

Phosphofructokinase

PFKL

21:45

No

Pfkl

10:77

No

 

PFKM

12:47

No

Pfkm

15:98

No

 

PFKP

10:3

No

Pfkp

13:7

No

Aldolase

ALDOA

16:30

Yes (2)

Aldoa

7:127

Yes (18)

 

ALDOB

09:103

No

Aldob

4:50

No

 

ALDOC

17:24

No

Aldoc

11:78

No

Triosephosphate isomerase

TPI1

12:7

Yes (4)

Tpi1

6:125

Yes (15)

Glyceraldehyde 3-phosphate dehydrogenase

GAPDH

12:7

Yes (52)

Gapdh

6:125

Yes (188)

 

GAPDHS

19:41

No

Gapdhs

7:30

No

Phosphoglycerate kinase

PGK1

X:77

Yes (3)

Pgk1

X:102

Yes (11)

Phosphoglycerate mutase

PGAM1

10:99

Yes (21)

Pgam1

19:42

Yes (12)

 

PGAM2

07:44

No

Pgam2

11:6

No

 

PGAM5

12:132

No

Pgam5

5:111

Yes (1)

Enolase

ENO1

01:9

Yes (4)

Eno1

4:149

Yes (27)

 

ENO2

12:7

No

Eno2

6:125

No

 

ENO3

17:5

No

Eno3

11:70

No

 

ENO4

10:119

No

Eno4

19:59

No

Pyruvate kinase

PKLR

01:154

No

Pklr

3:89

No

 

PKM2

15:70

Yes (6)

Pkm2

9:59

Yes (17)

Ensembl release 48 Dec 2007

      
  1. The Position column indicates chromosomal location denoted as "chromosome number:position (millions)". The Ret. seq. column indicates whether retroposed sequences were identified for each parent gene. The number in parentheses next to "Yes" in this column indicates the total number of retroposed sequences that match the parent gene. We identified a total of 94 retroposed sequences matching glycolytic enzymes in the human genome and 291 in the mouse genome.