Table 3 Altered levels of miRNA biogenesis and miRISC components in K562 and HL60.
From: Analysis of microRNA transcriptome by deep sequencing of small RNA libraries of peripheral blood
Protein | Function | K562/Normal (Fold Change) | HL60/Normal (Fold Change) |
|---|---|---|---|
DROSHA (RNASEN) | PrimiRNA processing | 2.238954 | 2.017825 |
DGCR8 | PrimiRNA processing | 2.078018 | Unchanged |
XPO5 | Exporting premiRNA | 2.669646 | 2.199101 |
RAN | Exporting premiRNA | 1.832214 | Unchanged |
DICER1 | PremiRNA processing | -1.79971 | Unchanged |