Venn diagram showing distribution of BLAST matches. Amino acid level homologies with bitscore of 50 or better were considered. (A) A. caninum transcripts homologous to B. malayi and C. elegans. Only 23% of the transcripts (11,025/48,326) shared homology, leaving 37,301 transcripts to be specific to A. caninum. (B) B. malayi genes homologous to A. caninum and C. elegans. About 62% of the 11,609 B. malayi genes shared homology. Higher number of B. malayi genes had homologs to the parasitic A. caninum compared to the free-living C. elegans, and 4,406 B. malayi genes did not share homology.