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Table 2 Differentially regulated genes regarding the cell cycle process after B[a]P exposure.

From: Benzo(a)pyrene induces similar gene expression changes in testis of DNA repair proficient and deficient mice

Symbol

Gene Name

Wt

Xpc -/-

Bin3

bridging integrator 3

1.13

1.31

Brca2

breast cancer 2

-1.35

-1.34

Brms1

breast cancer metastasis-suppressor 1

-1.18

-1.34

Calr

calreticulin

-1.26

-1.31

Ccnb2

cyclin B2

-1.24

-1.16

Ccng2

cyclin G2

1.23

1.32

Ccnk

cyclin K

1.21

1.23

Cdc25c

cell division cycle 25 homolog C (S. cerevisiae)

-1.09

-1.30

Cdc27

cell division cycle 27 homolog (S. cerevisiae)

1.41

1.31

Cdc42

cell division cycle 42 homolog (S. cerevisiae)

1.34

1.50

Cdca1

cell division cycle associated 1

1.24

1.50

Cdca5

cell division cycle associated 5

1.18

1.30

Cdca8

cell division cycle associated 8

-1.24

-1.11

Cdk5rap3

CDK5 regulatory subunit associated protein 3

-1.24

-1.23

Cetn1

centrin 1

1.46

1.31

Cit

citron

1.20

1.35

Cks2

CDC28 protein kinase regulatory subunit 2

1.29

1.36

Cul3

cullin 3

1.28

1.18

Dhcr24

24-dehydrocholesterol reductase

1.50

1.43

Dnajc2

DnaJ (Hsp40) homolog, subfamily C, member 2

-1.42

-1.23

Fzr1

fizzy/cell division cycle 20 related 1 (Drosophila)

1.44

1.39

Gspt1

G1 to S phase transition 1

1.37

1.31

Hells

helicase, lymphoid specific

1.43

1.46

Incenp

inner centromere protein

1.17

1.29

Kif20a

kinesin family member 20A

1.54

1.41

Macf1

microtubule-actin crosslinking factor 1

1.16

1.49

Mad2l2

MAD2 mitotic arrest deficient-like 2 (yeast)

1.19

1.27

Mphosph6

M phase phosphoprotein 6

1.30

1.26

Mtus1

mitochondrial tumor suppressor 1

-1.22

-1.19

Nasp

nuclear autoantigenic sperm protein (histone-binding)

1.34

1.38

Nek4

NIMA (never in mitosis gene a)-related expressed kinase 4

1.31

1.37

Pin1

protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1

1.31

1.26

Ppp3ca

protein phosphatase 3, catalytic subunit, alpha isoform

-1.19

-1.22

Pten

phosphatase and tensin homolog

1.32

1.31

Rad17

RAD17 homolog (S. pombe)

1.22

1.27

Ranbp1

RAN binding protein 1

-1.24

-1.23

Rbm5

RNA binding motif protein 5

1.34

1.39

Sgol1

shugoshin-like 1 (S. pombe)

1.26

1.20

Smarcb1

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1

1.27

1.33

Sycp3

synaptonemal complex protein 3

1.34

1.30

Tacc3

transforming, acidic coiled-coil containing protein 3

1.31

1.34

Tipin

timeless interacting protein

-1.22

-1.24

Trrap

transformation/transcription domain-associated protein

-1.26

-1.22

Tubb6

tubulin, beta 6

-1.33

-1.44

Ube2i

ubiquitin-conjugating enzyme E2I

1.17

1.30

Zw10

ZW10 homolog (Drosophila), centromere/kinetochore protein

1.23

1.30

  1. 46 differentially regulated genes regarding the cell cycle process. Results are presented as average gene expression ratios between exposed and control samples.