Figure 5

Enrichment analysis of EC-restricted genes. A) Top enriched Canonical Pathways B) Top enriched GO Processes. C) Top enriched disease set. The analysis for pathways and disease set enrichment was performed using the MetaCore tool of the GeneGo package. The GO categories enrichment analysis was performed using the DAVID tool. The Bar graphs depict the enriched pathway or Go process categories and -log of the P value. The P value depicts the significance of enrichment, the smaller is the P value the more significant is the enrichment. The pathways and disease sets with FDR adjusted P value < 0.05 are considered significant. The panel for gene ontology enrichment depicts the enrichments for each GO category (-log P value) as well as the Escore for a cluster of related GO categories.