Table 4 Identification of transcription factor binding sites (TFBSs) present in TFAP2A- modulated genes by over-represented DNA oligonucleotides.
From: Identification of functional TFAP2A and SP1 binding sites in new TFAP2A-modulated genes
| TFAP2A-regulated genes | Over-represented oligo | TF | Target genes | p (Fisher test) |
|---|---|---|---|---|
| DOWN n = 157 | CGGGC* | AP-2alpha, C-Rel, MYB, AMEF-2 | 22 | 1.20E-07 |
| GAGCCGGC | 27 | 1.48E-07 | ||
| CCCGC* | OLF-1, AP-2alpha, Sp-1,TCF-1(P),EGR | 38 | 7.76E-07 | |
| CCCGGC* | AP-2alpha, MTF-1 | 47 | 1.20E-06 | |
| CCCCGAGG* | AP-2alpha | 51 | 4.57E-06 | |
| CGGCA* | AP-2alpha | 57 | 7.08E-06 | |
| CCCATCCTA | 64 | 1.17E-05 | ||
| CGGCAGCC | 65 | 1.51E-05 | ||
| GCCCGC* | AP-2alpha | 66 | 2.45E-05 | |
| CGGGTGCTC | 70 | 2.75E-05 | ||
| UP n = 107 | AAGCGCG* | 6 | 8.32E-06 | |
| GGGGACTAA | 11 | 1.62E-05 | ||
| AGACGTCT | 16 | 2.04E-05 | ||
| AAACAACAG* | 21 | 4.27E-05 | ||
| ACCCACGCG* | 26 | 5.13E-05 | ||
| CGGGGTAGA | 29 | 5.89E-05 | ||
| CCTGTTTCG* | 33 | 6.92E-05 | ||
| CCGGAG | 40 | 7.08E-05 | ||
| ACGGGTTCT | 42 | 7.59E-05 | ||
| CCGGAGGC | AP-2alpha | 43 | 8.13E-05 |