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Table 6 Identification of transcription factor binding sites (TFBSs) present in TFAP2A- modulated genes by MEME analysis.

From: Identification of functional TFAP2A and SP1 binding sites in new TFAP2A-modulated genes

TFAP2A-regulated genes MEME regular expression TF Target genes MEME E-value
DOWN n = 157 [GA]CCTGTA[AG]TCCCAGC[TA][CA][CT]T[TC] PITX2, CRX 26 9.1E-162
  AT[CT]CTCC[TC][GA]CCTC[AG]G   34 2.6E-058
  T[CG][CG]A[GC][TA]CCAGCCTGG[GC]C[AG]AC   29 4.3E-104
  AGG[TC]TGCAGTGAGC[CT]G[AT]GAT Sp-1, AP-2apha, MAZ, TFII-I 24 3.1E-085
  GG[GA]GG[CA]GGGG[CGA][GC]GG[GA][GAC]G[GAC]GG   38 1.7E-056
  GTGAGCCAC[CT][GA]CGCCCGGC[CT]   21 2.0E-049
UP n = 107 CTCCC[AG]A[AG][GT][TA]GCTGGGA[TC]TA MYOD, PITX2, CRX 20 2.1E-126
  GT[CT]TC[AG]C[TC][AC]TGT[TC][GA][CG]CCAGG YY1, AP-2alpha 22 1.5E-082
  G[GC]GGCGG[GC]G[GC][CG]GG[GC]GG[CG]GG[GC] Sp-1, AP-2alpha 35 9.7E-062
  [GT]TGTGTGTG[TC]G[TC][GA][TC]GTGTG[TG] MYC 9 3.2E-016
  G[GC][TC]TCAAG[CT]GAT[TC]CTCC[TC]GC NKX2-5 16 1.5E-049
  CAGG[CT]G[TC]G[AC]GCCACC[GA]C[GA]CC AREB6, AML1 19 7.7E-067
  ATCT[CT][GA]GCTCACTGCA[AG]CCT   16 9.8E-048
  TGGTCTCGA[TA]CTCCTGACCT T3R, ER 12 8.0E-032
  1. For each TF its consensus binding site sequence, abbreviated name, number of target genes and statistical enrichment values (E-value) are reported.