Table 2 Significant associations between gemcitabine IC50 values and CNV regions.
From: Copy number variation and cytidine analogue cytotoxicity: A genome-wide association approach
CNV ID | Permutation P-value | Chromosome: Region | Number of SNPs | Length(bp) | SNP start-SNP end | Nearest Gene(s) |
|---|---|---|---|---|---|---|
chr9CNV58 | 0.027 | chr9:12005741-12098916 | 23 | 93176 | rs10809674-rs12351590 | TYRP1 |
chr1CNV5 | 0.031 | chr1:187795066-187809352 | 4 | 14287 | rs382645-rs269747 | FAM5C |
chr14CNV87 | 0.036 | chr14:106047919-106066496 | 2 | 18578 | rs4562969-rs10151262 | ADAM6 |
chr11CNV74 | 0.042 | chr11:134154053-134211153 | 25 | 57101 | rs1289444-rs2155304 | B3GAT1 |
chr11CNV65 | 0.043 | chr11:5858528-5889688 | 12 | 31161 | rs1377518-rs1453428 | OR52E4 |