Figure 2

Overlap between transcription factors and their binding motifs. Transcription factor overlap between the 119 transcription factors included on the RAT230 2 chip and their binding motifs contained in TRANSFAC or JASPAR. A. Circle to the left represents the set of transcription factors included on the RAT230 2 chip, in total 119 of which 34 are differentially expressed. TRANFAC contains DNA binding motifs of 541 distinct transcription factors, 29 of which are on the array. Of these 6 are differentially expressed (green) and 23 are non-differentially expressed (red). Thus 28 (grey) differentially expressed transcription factors do not have binding motifs in TRANFAC, which on the other hand contains binding motifs of 512 transcription factors not contained on the microarray (yellow). B. Overlap between the transcription factors included on the RAT230 2 chip and their biding motifs contained in JASPAR. Same color code as in A.