Heatmap of core and accessory orthologs found in V. cholerae N16961 and their distribution among the sequenced Vibrionaceae strains. The large (top) and small (bottom) chromosomes of the 11 strains are represented. Vertical blue or yellow bars represent the presence or absence, respectively, of each orthologous group in each genome. Vertical black bars represent proteins that are unique to V. cholerae N16961. The orthologous groups are arranged according to the encoding gene order on the V. cholerae N16961 chromosomes. Previously characterized genomic islands and the superintegron region are highlighted. The genomes are ordered top to bottom according to their phylogenetic relationships as shown in the dendrogram on the left. The dendrogram was calculated using the dollop algorithm from PHYLIP (see Methods) and is based on the presence or absence of the accessory orthologous groups.