Table 3 Pathway Express analysis of metabolic pathways and gene networks significantly affected by differentially expressed genes
From: Muscle transcriptomic profiles in pigs with divergent phenotypes for fatness traits
KEGG pathway-id | KEGG pathway name | IF† | input/pathway genes | pathway genes on chip | p-value* |
|---|---|---|---|---|---|
04612 | Antigen processing and presentation | 61.066 | 15/88 | 45 | 1.87E-25 |
►04070 | Phosphatidylinositol signalling system | 18.350 | 10/77 | 60 | 2.08E-07 |
►01040 | Biosynthesis of unsaturated fatty acids | 10.791 | 7/23 | 18 | 2.43E-04 |
05222 | Small cell lung cancer | 8.686 | 14/87 | 71 | 1.64E-03 |
04510 | Focal adhesion | 7.117 | 20/199 | 169 | 6.58E-03 |
05332 | Graft-versus-host disease | 6.966 | 6/42 | 22 | 7.52E-03 |
►04910 | Insulin signalling pathway | 6.430 | 16/138 | 114 | 1.20E-02 |
05310 | Asthma | 6.323 | 5/30 | 17 | 1.31E-02 |
04520 | Adherents junction | 5.957 | 6/75 | 69 | 1.80E-02 |
04514 | Cell adhesion molecules (CAMs) | 5.952 | 13/133 | 95 | 1.81E-02 |
05330 | Allograft rejection | 5.813 | 6/38 | 26 | 2.04E-02 |
►04930 | Type II diabetes mellitus | 5.556 | 6/44 | 33 | 2.53E-02 |
►04512 | ECM-receptor interaction | 5.211 | 10/87 | 72 | 3.39E-02 |
05320 | Autoimmune thyroid disease | 4.955 | 6/53 | 31 | 4.20E-02 |
04940 | Type I diabetes mellitus | 4.955 | 6/44 | 31 | 4.20E-02 |
04150 | mTOR signalling pathway | 4.932 | 7/51 | 42 | 4.28E-02 |
►04920 | Adipocytokine signalling pathway | 4.779 | 8/72 | 64 | 4.66E-02 |
►03320 | PPAR signalling pathway | 4.684 | 9/69 | 61 | 4.75E-02 |
►04350 | TGF-beta signalling pathway | 4.662 | 9/89 | 74 | 4.95E-02 |