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Table 1 Gene ontology analysis of genes expressed at higher levels in CD34+ cells

From: Expression of a retinoic acid signature in circulating CD34 cells from coronary artery disease patients

Molecular Function # genes p-value
Nucleic acid binding 440 1.41E-24
Transcription factor 328 6.13E-20
Zinc finger transcription factor 173 3.54E-16
KRAB box transcription factor 129 4.95E-16
Synthase and synthetase 63 1.93E-13
Transferase 154 1.13E-11
Synthase 37 1.97E-09
Methyltransferase 34 5.45E-05
Oxidoreductase 93 9.25E-05
Hydrolase 105 5.66E-04
Lyase 32 1.23E-03
Kinase 97 1.43E-03
Transcription cofactor 35 2.58E-03
Synthetase 24 3.41E-03
Other miscellaneous function protein 68 3.98E-03
Nuclease 36 1.19E-02
DNA-directed DNA polymerase 10 1.30E-02
Translation initiation factor 17 1.81E-02
Select regulatory molecule 145 2.39E-02
DNA helicase 19 2.91E-02
Acetyltransferase 20 2.99E-02
Ligase 65 3.82E-02
Aminoacyl-tRNA synthetase 12 3.89E-02
  1. Molecular functions of genes which are upregulated in CD34+ cells compared to more differentiated hematopoietic cells (no significant pathways were identified).