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Table 5 CD630 genes found to be absent from all strains (except CD630 and ECDC 012)

From: Array comparative hybridisation reveals a high degree of similarity between UK and European clinical isolates of hypervirulent Clostridium difficile

Gene Synonym Function
CD0211-2 licC CTP:phosphocholine cytidylyltransferase; putative choline sulfatase
CD0359 - 368   conjugative transposon conserved hypothetical protein; putative transcriptional regulator; two-component system; sensor histidine kinase; two-component system; response regulator; putative lantibiotic ABC transporter; membrane protein; putative lantibiotic ABC transporter;ATP-binding protein; putative lantibiotic ABC transporter; permease protein; putative lantibiotic ABC transporter;ATP-binding protein; two-component system; sensor histidine kinase; two-component system; response regulator
CD0370   putative transcriptional regulator
CD0381-2   putative conjugative transposon replication initiation factor; putative membrane protein
CD0385   putative membrane protein_conjugative transposon protein
CD0495   putative regulatory protein (pseudogene)
CD0498-9 orf21; orf20 conjugative transposon FtsK/SpoIIIE-family protein; putative conjugative transposon replication initiation factor
CD0503-4 orf15; orf14 conjugative transposon membrane protein; putative cell wall hydrolase
CD0906-907A   putative phage DNA-binding protein; putative phage regulatory protein; putative phage regulatory protein
CD0921   hypothetical phage protein
CD0925-6   hypothetical phage protein; hypothetical phage protein
CD0930-32   phage protein; hyypothetical phage protein; hyypothetical phage protein; hyypothetical phage protein
CD0935   phage modification methylase
CD0958-9   putative oxidoreductase (pseudogene); putative oxidoreductase (pseudogene)
CD0967   hypothetical phage protein
CD0970-1   putative oxidoreductase (pseudogene); putative oxidoreductase (pseudogene)
CD0971   putative oxidoreductase (pseudogene)
CD0975-7   putative oxidoreductase (pseudogene); putative oxidoreductase (pseudogene); putative oxidoreductase (pseudogene)
CD1092A   two-component sensor histidine kinase (pseudogene)
CD1094-99   two-component sensor histidine kinase (pseudogene);
putative lantibiotic ABC transporter; permease protein;
two-component sensor histidine kinase (pseudogene);
two-component sensor histidine kinase (pseudogene);
two-component sensor histidine kinase (pseudogene)
CD1102-6   two-component sensor histidine kinase (pseudogene);
two-component sensor histidine kinase (pseudogene);
two-component sensor histidine kinase (pseudogene);
two-component sensor histidine kinase (pseudogene);
two-component sensor histidine kinase (pseudogene)
CD1110   two-component sensor histidine kinase (pseudogene)
CD1112   two-component sensor histidine kinase (pseudogene)
CD1115-8   two-component sensor histidine kinase (pseudogene);
two-component sensor histidine kinase (pseudogene);
two-component sensor histidine kinase (pseudogene);
two-component sensor histidine kinase (pseudogene)
CD2001   conserved hypothetical protein
CD2003-5 effD; effR putative efflux pump; MarR-family transcriptional regulator; conserved hypothetical protein
CD2793 slpA cell surface protein (S-layer precursor protein)
CD2890-3   putative oxidoreductase (pseudogene); putative oxidoreductase (pseudogene); putative oxidoreductase (pseudogene); putative oxidoreductase (pseudogene)
CD2897   putative oxidoreductase (pseudogene)
CD2905-7   putative oxidoreductase (pseudogene); putative oxidoreductase (pseudogene); putative oxidoreductase (pseudogene)
CD3136-8 bglA3 6-phospho-beta-glucosidase; PTS system; IIabc component; transcription antiterminator
CD3147-53   putative DNA-methyltransferase; hypothetical protein;
putative DNA helicase; conserved hypothetical protein;
putative phage protein; conserved hypothetical protein;
putative phage transcriptional regulator; putative phage
DNA-binding protein
CD3326   Integrase
CD3331-3   hypothetical protein; TetR-family transcriptional regulator
CD3341-2   conjugative transposon conserved hypothetical protein (pseudogene); putative phage membrane protein
CD3344   conjugative transposon-related FtsK/SpoIII-relatd protein
CD3347-8   putative membrane protein; conserved hypothetical protein