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Table 3 Upregulated genes in the cluster containing AZFc deleted samples as classified on the basis of their main biological functions.

From: Testis transcriptome analysis in male infertility: new insight on the pathogenesis of oligo-azoospermia in cases with and without AZFc microdeletion

General biological function

Specific biological function

Upregulated genes in AZFc deleted patients cluster

Cellular growth and proliferation

Proliferation of eucariothic cell

A2M, ADAMTS1, AIF1, ANGPTL1, CEBPD, COL4A1, DCN, GSTM1, HIF1A, HMGB1, ICMT, IL6ST, KIF3A, LY96, NKX3-1, PLAU, PTK2, S100B, SOD2, SPTBN1, TPT1

Reproductive system development and function

Reproductive process of mammalia

DDX3Y (DBY), IL6ST, PLAU, UTY

Cell death

apoptosis of eukaryotic cells

A2M, ANGPTL1, C7, CEBPD, DCN, HIF1A, HMGB1, ICMT, IL6ST, KIF3A, PLAU, PTK2, SOD2, TPT1, YES1