Mobile genetic element proliferation and gene inactivation impact over the genome structure and metabolic capabilities of Sodalis glossinidius, the secondary endosymbiont of tsetse flies

Table 2 Functional status of genes involved in thiamine diphosphate biosynthesis in S. glossinidiu s and W. glossinidi a.

		S. glossinidius			W. glossinidia
Gene name	Enzyme	Gene	Pseudog.	Absent	Gene	Pseudog.	Absent
*thiI*	Sufur-carrier protein ThiI	+					+
*thiF*	Thiamin (thiazole moiety) biosynthesis protein ThiF	+				+
*iscS*	Cysteine desulfurase	+					+
*thiS*	Sulfur-carrier protein ThiS		+		+()**
*dxs*	1-deoxyxylulose-5-phosphate synthase	+			+
*thiG*	ThiG subunit of thiamin biosynthesis complex ThiGH		+		+
*thiH*	ThiH subunit of thiamin biosynthesis complex ThiGH		*+()**		+
*thiC*	Thiamin (pyrimidine moety) biosynthesis protein ThiC		+		+
*thiD*	Bifunctional hydroxymethylpyrimidine kinase/phosphohydroxymethylpyrimidine kinase			+	+
*thiE*	Thiamin phosphate synthase		+		+
*ybjQ*	Conserved protein with activity thiamin phosphate synthase	+					+
*thiL*	Thiamin-monophosphate kinase	+			+
*thiM*	Hydroxyethylthiazole kinase	+					+
*thiK*	Thiamin kinase	+					+
*tenA2*	Thiaminase	+					+
*thiP*	Thiamin ABC transport system; fused membrane components	+					+
*thiQ*	Thiamin ABC transport system; ATP-binding protein	+					+
*tbpA*	Thiamin ABC transport system; substrate-binding protein	+					+

^(*) Originally annotated gene with premature stop codon
^(**) Gene absent in W. glossinidia in original annotation but detected in the present study by TBLASTN against E. coli K12 genome

ISSN: 1471-2164