Table 5 Summary of TF connectivity
From: A systems approach to mapping transcriptional networks controlling surfactant homeostasis
TFBS | Total Connectivity | C1 | C2 | C28 | TF in Lung |
|---|---|---|---|---|---|
CEBP | 447 | 238 | 51 | 158 | Cebpa, Cebpb, Cebpd, Cebpg |
IRFF | 404 | 239 | 0 | 165 | Irf1, Irf2, Irf3, Irf5, Irf7 |
HNF3 | 359 | 228 | 51 | 80 | Foxa1, Foxa2 |
GATA | 358 | 218 | 44 | 96 | Gata6, Gata1 |
ETSF | 344 | 172 | 14 | 158 | Ets1, Ets2, Etv5, Nfe2l2, Elf2 |
SREB | 312 | 162 | 43 | 107 | Srebf1 |
FOXO | 268 | 151 | 0 | 117 | Foxo1, Foxo4, Foxo3a |
FKHD | 213 | 95 | 25 | 93 | Foxf2, Foxc1 |
HAND | 201 | 94 | 0 | 107 | Lmo2 |
STAT | 182 | 0 | 0 | 182 | Stat6, Stat3 |
MEF2 | 176 | 110 | 0 | 66 | Mef2a |
NFAT | 169 | 0 | 0 | 169 | Ilf3, Nfatc3 |
CP2F | 168 | 83 | 0 | 85 | Atf4, Tcfcp2, Atf3, Atf1 |
NFKB | 166 | 78 | 0 | 88 | Nfkb1 |
EREF | 165 | 113 | 0 | 52 | Esrra |
LEFF | 150 | 97 | 0 | 53 | Lef1 |
HFH | 134 | 75 | 19 | 40 | Foxf1a, Foxi1 |
PARF | 134 | 134 | 0 | 0 | Tef, Tead1 |
AP1R | 129 | 60 | 0 | 69 | Nfe2 |
LEFF | 121 | 87 | 34 | 0 | Tcf4 |
CIZF | 117 | 117 | 0 | 0 | Znf384 |
HAND | 113 | 43 | 0 | 70 | Tcf12 |
BARBIE | 111 | 98 | 13 | 0 | Unknown |
NKXH | 106 | 68 | 38 | 0 | Nkx2-1 |
SORY | 104 | 93 | 11 | 0 | Sox5, Sox9 |
NR2F | 98 | 37 | 20 | 41 | Hnf4a, Nr2f1, Nr2f2 |
OCT | 92 | 92 | 0 | 0 | Pou2f1, Pou6f2 |
CREB | 79 | 0 | 10 | 69 | Creb1 |
MYOD | 74 | 0 | 0 | 74 | Myog |
NKX7 | 62 | 39 | 0 | 23 | Nkx6-2 |
EBOX | 59 | 0 | 21 | 38 | Tcf4, Max |
P53F | 57 | 0 | 0 | 57 | Trp53 |
RORA | 57 | 0 | 0 | 57 | Rora |
HAML | 54 | 0 | 0 | 54 | Runx2, Pebp1 |
RXRF | 54 | 0 | 0 | 54 | Nr1h2 |
GREF | 48 | 48 | 0 | 0 | Nr3c1 |
BRN5 | 46 | 25 | 0 | 21 | Pou6f1 |
HESF | 46 | 0 | 20 | 26 | Hes1 |
EGRF | 45 | 0 | 45 | 0 | Egr1, Wt1 |
HOXH | 44 | 0 | 0 | 44 | Meis1 |
SPIF | 39 | 0 | 39 | 0 | Klf11 |
HNF1 | 38 | 0 | 38 | 0 | Hnf1a, Hnf1b, Hmbox1 |
E2FF | 33 | 0 | 33 | 0 | E2f1, E2f2, E2f3, E2f4, E2f5, E2f7 |
SMAD | 23 | 0 | 23 | 0 | Smad4 |
ZBPF | 23 | 0 | 23 | 0 | Zfp219 |
NKX6 | 22 | 22 | 0 | 0 | Nkx6-1 |
LXHF | 21 | 21 | 0 | 0 | Lxh3 |
AP2F | 19 | 0 | 19 | 0 | Tcfap2c |
PTBP | 19 | 0 | 19 | 0 | Tbp |
GLIF | 16 | 0 | 16 | 0 | Zic2 |
BCDF | 15 | 0 | 15 | 0 | Crx |
SPZ1 | 11 | 0 | 11 | 0 | Spz1 |
PAX2 | 10 | 0 | 10 | 0 | Pax2 |
MTF1 | 9 | 0 | 9 | 0 | Mtf1 |
ZF5F | 8 | 0 | 8 | 0 | Zfp161 |