Table 1 Allele-specific splicing candidates.
Gene | Exon Included Reads (B6:CAST) | Exon Skipped Reads (B6:CAST) | p(ASE) is less than* | Gene function (Gene Ontology) | Conserved protein domain encoded by skipped exon (Pfam) |
|---|---|---|---|---|---|
Slc8a1 | 6 (2:4) | 429 (232:197) | 0.344 | reduction of cytosolic calcium ion concentration | No domain reported |
Baz2b | 30 (9:21) | 99 (58:41) | 0.021 | chromatin modification | Bromodomain adj. to zinc finger domain (PTHR22880) |
Eif4enif1 | 24 (3:21) | 18 (12:6) | 0.119 | protein transport | No domain reported |
Epb4.1l2 | 7 (5:2) | 6 (2:4) | 0.344 | cortical actin cytoskeleton organization | 4.1 C-terminal domain (PF05902) |
Papd4 | 6 (6:0) | 3 (0:3) | 0.125 | polynucleotide adenylyltransferase activity | PAP/OAS1 substrate-binding domain (SSF81631)) |
Aqr | 8 (8:0) | 3 (0:3) | 0.125 | RNA splicing; body morphogenesis | DNA2/NAM7 helicase family member (PTHR10887:SF5) |
Ankrd12 | 32 (9:23) | 3 (3:0) | 0.125 | unknown | Ankyrin repeat (SSF48403) |
Nudc | 27 (11:16) | 75 (75:0) | 0.221 | nuclear migration; nervous system development | CS (PS51203), HSP20-like chaperones (SSF49764) |
Rbm17 | 32 (16:16) | 5 (5:0) | 0.031 | mRNA processing, RNA binding | Splicing factor 45 (PTHR13288:SF9) |
Cacna1h | 1118 (378:740) | 5 (5:0) | 0.031 | Calcium transport | Voltage-gated_potassium_channels (SSF81324) |